

Do you want to do more than just treat the pain of your patients’ dentine hypersensitivity?
Sensodyne Repair & Protect is the first Sensodyne daily fluoride toothpaste with advanced desensitising technology, building a substantive reparative layer over exposed dentine using the natural building blocks of teeth1-6.
NovaMin® is an advanced calcium phosphate technology and employs the same patented bioactive material used in advanced bone regeneration techniques7.


In vitro cross-section Scanning Electron Microscope (SEM) image of hydroxyapatite-like layer formed by supersaturated NovaMin® solution
in artificial saliva after 5 days (no brushing). Adapted from8.
Hydroxyapatite-like crystals form a reparative layer

In vitro SEM images of etched human dentine tubules pre- and post-application of NovaMin® in artificial saliva. Adapted from8.
Starting to form from the first use8, the reparative layer creates an effective and lasting barrier to the pain of dentine hypersensitivity, with twice-daily
brushing9-11. This layer, which is harder than natural dentine1,12, is resistant to toothbrush abrasion and to typical acid challenges found in patients’ typical diets1,4,5,13,14.
Now your patients can continuously help repair, strengthen and protect against dentine hypersensitivity with Sensodyne… every day.
For further information on Sensodyne Repair & Protect contact your GSK Healthcare Territory Manager.
References:
1. Burwell A et al. of Clinical Dentistry 2010; 21(Special Issue): 66-71.
2. LaTorre G & Greenspan DC. Journal of Clinical Dentistry 2010; 21 (Special Issue): 72-76.
3. Ogino M et al. of Biomedical Materials Research 1980; 14: 55-64.
4. GlaxoSmithKline data on file SF/EU/04/10 Parkinson C, 2010.
5. GlaxoSmithKline data on file SF/EU/08/10 Earl J, 2010.
6. Hall RC et al. : Addy M et al (eds). Tooth wear and sensitivity, pp 3-18. London: Martin Dunitz, 2000.
7. Greenspan DC. Journal of Clinical Dentistry 2010; 21(Special Issue): 61-65.
8. GlaxoSmithKline data on file SF/EU/05/10 Earl J, 2010.
9. Du MQ et al. Journal of Dentistry 2008; 21(4): 210-214.
10. Pradeep AR & Sharma A. Journal of Periodontology 2010; 81(8):1167-1173.
11. Salian S et al. Journal of Clinical Dentistry 2010; 21 (Special Issue): 82-87.
12. GlaxoSmithKline data on file SF/EU/03/10 Parkinson C, 2010.
13. GlaxoSmithKline data on file SF/EU/09/10 Earl J, 2010.
14. Wang Z et al. Journal of Dentistry 2010; 38: 400-410.
SENSODYNE, NOVAMIN and the rings device are registered trade marks of the GlaxoSmithKline group of companies.